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Email this article Effects of maternal linseed oil supplementation on oxidative stress markers in cafeteria diet induced obese rats
Abstract
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We investigated the role of dietary linseed oil in the modulation of biochemical parameters and oxidant/antioxidant markers in cafeteria-induced obese rats and their offspring. Female wistar rats were fed on control or cafeteria diet, supplemented or not with linseed oil (5%) for one month before and during the gestation. At parturition, the mothers and their offspring were killed. Weight gain, food intake, serum biochemical and oxidant/antioxidant markers were determined. Cafeteria diet induced a significant increase in body weight, food intake and adverse alterations in biochemical parameters such as an increase in serum glucose, triglyceride, cholesterol and oxidant markers. Linseed oil supplementation induced a reduction in weight gain, serum lipids and a modulation of oxidative stress, improving metabolic status. In conclusions, linseed oil displayed remarkable health benefits by decreasing plasma and oxidant/antioxidant markers in both obese mothers and their newborns.
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