Published October 29, 2018 | Version v1
Journal article Open

Synthesis and Evaluation of Biological Activity of Novel Sugar-Derived Aziridines

  • 1. Laboratoire de Chimie Organique, Substances Naturelles et Analyses (COSNA). Université de Tlemcen. Algérie
  • 2. Laboratoire de microbiologie appliquée à l'agroalimentaire au biomédical et a l'environnement (LAMAABE), Université de Tlemcen. Algérie.
  • 3. Faculté des Sciences, Université de Tlemcen. Algérie

Description

The Sugar derived aziridine was obtained from iodo-aziridines through in situ  nucleophilic expulsion of iodine using glucosamine as a nucleophile. This work describes new results of our ongoing research targeting new aziridines of  biological interest. All the compounds were screened for their antibacterial activity, they all showed comparable moderate to good growth inhibitory activity with reference to Tetracyclin, Ciprofloxacine and Gentamicin.

Files

AJNP-08-2018-final.pdf

Files (710.8 kB)

Name Size Download all
md5:07c9dfeb3af2e12c416b80a60d60d9e9
710.8 kB Preview Download