Evaluation of the Antibacterial Activity of the Sesamum alatum plant through Phytochemical Screening

Juliao Armando Monjane


The present work aimed to evaluate the antibacterial activity of the Sesamum alatum plant based on the screening of secondary metabolites present on the aqueous (H) and ethanolic (A) extracts of the leaves (F) and seeds (S). The biological assay was performed on the following microorganisms: Pseudomonas aeruginosa, Staphylococcus aureus, sensitive Escherichia coli, and multi-resistant E. coli using the disk diffusion method and the phytochemical analysis were performed based on the layer chromatography technique. From the crude extracts prepared and tested, a positive result was observed in the extracts SA and FH against E. coli mult and FA against P. aeruginosa, while the SH crude extract was inactive against all the strain tested. The active extracts were fractionated. The following fractions: FH-DCM (P. aeruginosa and S. aureus), SH-Et OAc (E. coli mult), and SH-DCM (S. aureus and E. coli mult) were active. Ciprofloxacin was used as a positive control. Phytochemical screening revealed the presence of flavonoids, alkaloids, glycosides, and terpenes in the plant. These results could justify the use of this plant in the traditional medicine.


Sesamum alatum; Antibacterial activity, Phytochemical screening

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