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Email this article Antibacterial Activities of New Compounds Nitrogen Heterocyclic Saturated
Abstract
This work describes the synthesis, spectroscopic, structural characterization and antibacterial activities of new saturated heterocyclic nitrogen compounds of the 1, 3, 5-triazacyclohexane type.
    The new triazacyclohexanes (R3TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:1 mixture of 4-iodoaniline and 2-ethyl1-hexyl amine with formalin. The synthesized compounds were characterized by spectral analysis IR, 1H NMR and 13C NMR and shown to be mainly a mixture of the two mixed triazacylcohexane.
   These compounds were screened for their antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.Â
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References
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M. Chebbah, A. Messai, D. Bilge, A. Bouchemma, C. Parlak. New unsymmetrically substituted triazacyclohexanes. Synthesis,characterisation, antimicrobial properties and DFT study, Journal of Molecular Structure 1129 (2017) 152-159
Ponce A.G., Fritz R., del Valle C. et Roura S.I. Antimicrobial activity of essential oils on the native microflora of organic Swiss chard, Lebensm.-Wiss.u.- Technol.36(2003), p.679-684.
in the 23S rRNA Gene and
Loss of a Single Copy of rRNA, J. Infect. Dis. DrugTargets, 190 (2004) 311-317
M. Chebbah, A. Messai, D. Bilge, A. Bouchemma, C. Parlak. New unsymmetrically substituted triazacyclohexanes. Synthesis,characterisation, antimicrobial properties and DFT study, Journal of Molecular Structure 1129 (2017) 152-159.
Ponce A.G., Fritz R., del Valle C. et Roura S.I. Antimicrobial activity of essential oils on the native microflora of organic Swiss chard, Lebensm.-Wiss.u.- Technol.36(2003), p.679-684.
DOI: http://dx.doi.org/10.5281/zenodo.889066
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