Published October 29, 2018
| Version v1
Journal article
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Synthesis and Evaluation of Biological Activity of Novel Sugar-Derived Aziridines
- 1. Laboratoire de Chimie Organique, Substances Naturelles et Analyses (COSNA). Université de Tlemcen. Algérie
- 2. Laboratoire de microbiologie appliquée à l'agroalimentaire au biomédical et a l'environnement (LAMAABE), Université de Tlemcen. Algérie.
- 3. Faculté des Sciences, Université de Tlemcen. Algérie
Description
The Sugar derived aziridine was obtained from iodo-aziridines through in situ nucleophilic expulsion of iodine using glucosamine as a nucleophile. This work describes new results of our ongoing research targeting new aziridines of biological interest. All the compounds were screened for their antibacterial activity, they all showed comparable moderate to good growth inhibitory activity with reference to Tetracyclin, Ciprofloxacine and Gentamicin.
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