Evaluation of the Anti-inflammatory Activity of Aqueous and Methanolic Extracts of Hibiscus sabdariffa and Camellia sinensis

Franklin Jesús Pacheco Coello, LILO FRANCO-DE JESUS


Hibiscus sabdariffa and Camellia sinensis are attributed with various properties or health benefits, among which stands out is its anti-inflammatory capacity associated with the presence of bioactive compounds such as flavonoids. The aim of the research was to evaluate the anti-inflammatory effect of the extracts aqueous and methanolic of H. sabdariffa and C. sinensis by inhibition of the enzyme cyclooxygenase-2. Vegetal material corresponding to calyxes of H. sabdariffa and leaves of C. sinensis were used to obtain the extracts. The Folin-Ciocalteu and Marinova method was used for the determination of total phenolic compounds and flavonoids. On the other hand, anti-inflammatory activity was carried out using a commercial kit and a gallic acid standard as a control.The results showed a higher percentage of inhibition in the methanolic extracts of each vegetable material. Statistical difference was observed when buying the aqueous and methanolic of H. sabdariffa (p=0.025), aqueous and methanolic of C. sinensis (p=0.035) extracts. These findings allow us to conclude that the anti-inflammatory activity of the extracts is related to the content of phenolic compounds present in the plant material and to the extraction method.


Hibiscus flower, Green Tea, Phenolic compounds, COX-2 inhibition

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